Ketamine Therapy in Chicago
Medically supervised, off-label ketamine sessions for depression, anxiety, PTSD and OCD, paired with therapeutic support in a private, comfortable room. The program reopens to new patients on December 1, 2026.
Are you already an Able Psychiatry patient?
Ketamine therapy in Lincoln Park
Reopening to new patients
Able Psychiatry offers off-label ketamine therapy in Chicago's Lincoln Park for depression, anxiety, PTSD and OCD. The program reopens to new patients on December 1, 2026. Sign up now with the ketamine questionnaire; current patients use the same form.
Personalized, compassionate care
At Able Psychiatry, we prioritize your comfort and sense of safety, with a supportive treatment environment, attentive staff care, and your active involvement in integrating what you experience during and after each session. We offer personalized recommendations based on your individual goals.
The importance of therapy with ketamine
We encourage therapy before starting ketamine treatment because it creates a strong foundation for your healing process. Therapy provides a safe space to explore underlying issues, set personal goals, and develop coping strategies, and to help you integrate the insights that arise during treatment.
Nine weeks, at your pace
One session per week, each lasting about two hours.
| Each session, patients seen within the practice | $250 |
| Each session, patients not seen within the practice | $350 |
| Cancelled less than 24 hours ahead | $175 |
| Missed without notice | $350 |
Financing through CareCredit.
Our ketamine therapy process
- 1
Initial consultation
Before starting treatment, you'll discuss with our staff which administration method is best for you: nasal spray, dissolvable lozenge (troche), or intramuscular injection.
- 2
Preparing for your session
On the day of your appointment, you'll settle into one of our comfortable ketamine rooms, where you can relax with music, visuals, or meditation.
- 3
Health monitoring
We begin each session by taking your resting blood pressure to ensure your safety throughout the treatment.
- 4
Ketamine administration
We'll guide you through the chosen method of ketamine administration and provide ongoing support as you enter a relaxed, trance-like state.
- 5
Self-guided exploration
During the session, you’ll embark on a personal journey of self-discovery, gaining new perspectives and insights. Our staff will be available to assist and check in as needed.
- 6
Post-session support
After your treatment, we provide guidance on integrating the experience and making the most of the tools and perspectives gained during your session.
What ketamine therapy can help
Ketamine for depression
Ketamine is used off-label for treatment-resistant depression. A 2017 psychiatric consensus statement found it can produce rapid antidepressant effects in some patients, but the supporting studies are small, with limited data on long-term efficacy and safety.
Ketamine for OCD
Ketamine is used off-label for OCD. A 2026 review found that the benefit of ketamine alone was usually short-lived, often fading within about a week.
Ketamine for anxiety
Ketamine is used off-label for anxiety disorders. A 2026 systematic review found preliminary evidence that ketamine or esketamine can reduce anxiety, especially with repeated maintenance doses, but symptoms may return after treatment stops and more research is needed.
Ketamine for PTSD
Ketamine is used off-label for treatment-resistant PTSD. In a small 2025 open-label study with no placebo group, PTSD symptom scores stayed low during six weeks of oral ketamine.
Ketamine therapy questions
How much does it cost?
Ketamine treatment costs $250 per session for patients seen within the practice, $350 per session for patients not seen within the practice. Each session must be paid out of pocket, before the appointment starts. We also offer financing through CareCredit. Appointments cancelled less than 24 hours in advance carry a $175 fee; a missed appointment without notice carries a $350 fee.
What is the purpose of ketamine?
In the mental health arena, ketamine is used off-label to treat symptoms of depression and PTSD.
It's important to note that ketamine is not a cure-all treatment. What it can do is help us gain new tools and perspectives to navigate and overcome challenges with greater choice and ease.
What will I feel or experience during my sessions?
Your experience during your ketamine sessions will be shaped by where you are on your personal timeline of growth and healing, and may change through your treatment. The most commonly reported experiences include feelings of happiness, calm, and relaxation. Some people experience visual or time distortions, or even the feeling they are out of their body. It is also common to feel you don't have full control over your mind and body, which may cause moments of brief anxiety.
What should I know before starting?
Limit alcohol use. Alcohol can interfere with the effectiveness of ketamine treatment. It’s best to reduce or avoid alcohol to experience the full benefits.
Expect a unique experience. Each person’s journey with ketamine is different, as we all have unique timelines for healing and growth. In the early stages, the focus may be on building safety and comfort before addressing deeper emotions, memories, or thoughts. This foundational work prepares you for deeper exploration later.
Know that anxiety is normal. It’s common to feel anxious during treatment, especially when you begin to dissociate. This sense of disconnect between mind and body can feel uncomfortable but is part of the process, helping your mind make necessary connections. Approach the experience with curiosity.
What are the side effects of ketamine therapy?
Minor side effects can include the following and tend to resolve within a few hours:
- Nausea or vomiting. To minimize this, stay well hydrated and avoid eating or drinking for 3 hours before treatment.
- Temporarily elevated blood pressure. The most common physical side effect is a short-term spike in blood pressure, pulse, or heart rate.
- Drowsiness and sedation
- Blurred vision
- Dizziness or lightheadedness
- Impaired balance and coordination
- Headache
Adverse side effects from high-dose, chronic use of ketamine are very rare in medically supervised settings. Tell your provider immediately if you notice frequent, painful, or difficult urination. Permanent bladder dysfunction or cystitis occurs when the drug is abused.
Psychologically, ketamine has been shown to worsen certain psychotic symptoms in people with schizophrenia or other serious mental disorders.
How long is treatment?
Our treatment is set up to last 9 weeks, with one session per week. Each session lasts about 2 hours. The number of treatments you complete is up to you; you are not obligated to continue the full 9 weeks.
How is it administered?
We have 3 administration options: nasal spray, troche (dissolvable lozenge), and intramuscular injection. Before starting treatment, you will discuss with Able staff which method is best for you.
What is a typical session like?
When you come to the office, you will get comfortable in one of our ketamine rooms. You are encouraged to listen to music, watch our TV visuals, meditate, or do whatever helps you relax. We start each appointment by taking your resting blood pressure and going over ketamine administration. During your session, you will embark on a self-guided exploration where you may learn more about yourself in unexpected ways. Throughout your appointment, Able Psychiatry staff are available to assist with any needs and will check in on you periodically.
How do I get the most from ketamine treatment?
The biggest way to benefit from ketamine treatment is to allow your mind to wander: be open to exploring whatever thoughts, feelings, or memories come up. It can help to set an intention or choose a topic you would like to explore before each session, which gives the mind a direction during your appointment.
There is no specific outcome needed or expected, just the opportunity to experience other perspectives on whatever your mind brings up, so you can consciously choose how to view and interpret it. If you can record insights from your session, they can be very useful to explore in future psychotherapy sessions.
How do I know if my ketamine treatment is working?
Gauging how your ketamine treatment is working depends on your own criteria. A common sign is being able to let things sit and allow them to be, without the need to take action, fix, or restrict. Other signs might include:
- Viewing things from a different perspective. For example, if you default to a common thought or behavior, do you sometimes also think of an alternative, even if you don't fully believe or follow it?
- Increased self-compassion or self-acceptance
- Increased compassion for or acceptance of others
These are just a few examples. Since every person's reasons for and expectations of treatment differ, so will the way they benefit.
How is this different from ketamine infusions?
Our ketamine treatment differs in cost, ease of administration and overall effect. Ketamine infusions often cost $350 to $500 or more per infusion. Infusions require an IV in the arm. Because the ketamine enters the bloodstream directly, the effects are felt almost immediately and much more intensely than with other methods. Depending on the patient, that may not be the best introduction to ketamine or its benefits.
At Able Psychiatry, our priority is your comfort and feeling of safety.
Will my current medications affect treatment?
Certain medications interact with ketamine and make it less effective. Tell us about all of your current medications so we can adjust for them.
What happens after I complete my treatment?
For the two months after your final session, we watch how the treatment effects are holding. You take part in two monthly check-in appointments, 30 and 60 days after your final ketamine session. These check-ins build on the work you've already done and help decide whether additional treatment cycles would be beneficial.
Sign up now
The ketamine program reopens to new patients on December 1, 2026. Sign up with the ketamine questionnaire, a short online form.
